DANIELLIA PHARMACOGNOSTIC AND BIOLOGICAL STUDIES OF THE ROOT OF OLIVERI (ROLFE) HUTCH. & DALZ. (CAESALPINIACEAE)
- Project Research
- 1-5 Chapters
- Abstract : Available
- Table of Content: Available
- Reference Style: APA
- Recommended for : Student Researchers
- NGN 3000
ABSTRACT
Daniellia oliveri is one of the most extensively utilized medicinal plants; it is a tree all of whose parts are used in Nigeria and some West African countries for the treatment of various ailments example the root is used as chewing stick. In the bid to standardize this plant, pharmacognostic and biological (anti-Candida) studies were carried out on its root and root bark. The anatomical and powdered samples of the root and root bark of D. oliveri were investigated for their microscopical profiles. The results indicated the presence of xylem and phloem tissues, parenchyma cells, cork cells, prisms of calcium oxalate crystals, abundant starch grains and secretory ducts. Phytochemical screening of the methanol extract and its fractions (ethyl acetate, n-butanol, and aqueous fractions) revealed the presence of carbohydrates, saponins, flavonoids, cardiac glycosides, steroids and tannins. The solvent system chloroform: methanol (7:3v/v) and n – butanol: acetic acid: water (2:1:2v/v) were found to be the best solvent systems for the separation of the constituents of the crude methanol extract and the different fractions using thin layer chromatography. Physico-chemical constants of the powdered root bark were determined; as 21.25+ 1.0 (total ash value), 21.75 + 1.0 (acid insoluble ash value), 11 + 1.0 (water soluble extractive value), 15.33+ 2.4 (alcohol soluble extractive value) and 7 + 1.0 (moisture content). The total phenolic content of the root bark extracts of D. oliveri were also determined; as 57±4.55mgg-l (Crude methanol extract), 59.33±6.65mgg-l (ethylacetate fraction), 60±5.72mgg-l (n-butanol fraction), 17±0.00mgg-l (aqueous fraction) and 12±2.94mgg-l (Crude water extract). The methanol extract showed an LD50 of 565.69mgkg-l i.p in rats. The crude methanol extract is fungicidal with minimal inhibitory concentration of 1.5675mgml-l and minimal fungicidal concentration of 50 and viii 12.5 mgml-l. The aqueous fraction from the methanol extract is fungistatic with minimal inhibitory concentration of 150mgml-l while the crude water extract, ethyl acetate and nbutanol fractions of the root bark of D. oliveri showed no anti Candida activity. The results obtained from this research can be used for the preparation of a monograph for proper identification of this plant.
Related Project Materials
EFFECTIVENESS OF ADVERTISING TOOLS FOR SUCCESSFUL MARKETING OF MTN PRODUCTS
EXCERPT FROM THE STUDY
Advertising is one of the four components of the marketing mix, which includes product, price, lo...
ASSESSMENT OF THE HOUSING CONDITION AND SOCIO ECONOMIC LIFESTYLES OF SLUM DWELLERS IN AKURE NIGERIA
STATEMENT OF THE PROBLEM
The process of urbanization which means specific changes in the distribution and structure of p...
Comparison of Academic Performance of Junior Secondary School students in English Language and integrated science in external examination
Abstract
The study compared the scores of students in English Language and Integrated Science at the Junior Secondary Sc...
SECURITY INFORMATION AND EVENT MANAGEMENT SYSTEM
ABSTRACT
The Security Information and Event Management (SIEM) enhances the security management of an organization by sto...
MANAGING RURAL DEVELOPMENT THROUGH INDUSTRALIZATION (A CASE STUDY OF AWGU LOCAL GOVERNMENT AREA)
Project Body
ABSTRACT
This research work scrutinized the impact of managing rural development...
MOLECULAR AND PATHOLOGICAL DIFFERENTIATION OF COLLETOTRICHUM TRUNCATUM FROM SCENTLESS CHAMOMILE AND LEGUME CROPS
ABSTRACT
The fungus Colletotrichum truncatum is a potential biocontrol agent (BA) against the noxious weed scentless chamomile (Metricari...
AN INVESTIGATION INTO THE IMPACT OF ACCOUNTING PRINCIPLES ON THE QUALITY OF FINANCIAL REPORTS OF FIRMS IN NIGERIA.
ABSTRACT
The study examines the relationship between accounting principles and quality of financial reports in Niger...
THE IMPACT OF VOCATIONAL EDUCATION ON REGIONAL ECONOMIC DEVELOPMENT
Abstract: The impact of vocational education on regional economic development is significan...
ADDRESSING THE MENTAL HEALTH NEEDS OF VOCATIONAL STUDENTS
Abstract: Addressing the mental health needs of vocational students is critical for promoti...
FIDUCIARY ACCOUNTING FOR CHARITABLE TRUSTS AND FOUNDATIONS
FIDUCIARY ACCOUNTING FOR CHARITABLE TRUSTS AND FOUNDATIONS
This research aims to (1) explore the fiduciary accounting pr...
